TTY Biopharm Co., Ltd.
NAIA Member(Famous Client)

 Company Profile Product
Product Name
Pegylated liposomal / Doxorubicin
Product Description

The treatment of AIDS-related Kaposi’s sarcoma in patients with low CD4 (<200 CD4 lymphocytes/mm³) and diseases in mucosa, skin and internal organs. The treatment of metastasis carcinoma of the ovary in patients with disease that is recurrent to both first-line platinum- and paclitaxel-based chemotherapy regimens. As monotherapy for patients with metastatic breast carcer, where there is an increased cardiac risk.

Product Name
Thalidomide
Product Description

THADO® (Thalidomide) may be used as an acute period treatment for patients showing moderate to severe ENL skin symptoms. It can also be used as continuous treatment for preventing and inhibiting the recurrent of ENL skin symptoms. The drug cannot be used alone for ENL patients with moderate to severe neuritis.

Product Name
Arsenic trioxide
Product Description

Arsenic Trioxide is indicated for acute promyelocytic leukemia ( APL ). Explanation: ASADIN is administered for induction of remission and consolidation in patients with acute promyelocytic leukemia ( APL ) who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy, and whose APL is characterized by the presence of the t ( 15 : 17 ) translocation or fusion protein PML/RARa gene expression. The efficacy of other acute myelogenous leukemia subtypes to Arsenic Trioxide has not been examined.

Product Name
Gemcitabine
Product Description

Its indications include non-small cell lung cancer NSCLC, pancreatic cancer, and bladder cancer. Gemcitabine and pacilitaxel may be combined for anthracycline-treated patents with locally-recurred breast cancer that is surgically no-resectable or metastatic. It can also be used in ovarian cancer that has been treated with platinum-based drugs buy recurs at an interval of more than 6 months, as second-line therapy.

Product Name
Tegafur-Uracil
Product Description

Gastric cancer, Colorectal cancer, Breast cancer, Squamous Cell Carcinoma of Head & Neck, and Combination with cisplatin is indicated for the treatment of patients with metastatic and advanced Lung cancer.

Product Name
Oxaliplatin
Product Description

In combination with 5-fluorouracil (5-FU) and folinic acid (FA) is indicated for: ?Adjuvant treatment of stage III (Duke's C) colon cancer after complete resection of primary tumor. ?Treatment of metastatic colorectal cancer. Oxaliplatin in combination with Capecitabine is indicated for the treatment of locally advanced and recurrent/metastatic gastric cancer.

Product Name
Irinotecan
Product Description

Irino is indicated for the treatment of patients with advanced colorectal cancer: - In combination with 5-fluorouracil and folinic acid in patients without prior chemotherapy for advanced disease. - As a single agent in patients who have failed an established 5-fluorouracil containing treatment regimen.

Product Name
Epirubicin
Product Description

Mammary carcinoma, malignant lymphoma, soft tissue sarcoma, and gastric, lung, ovarian carcinomas. 

Product Name
Anastrozole
Product Description

The product could be an assisted therapy for postmenopausal women with early invasive breast cancer, who have positive estrogen receptors; additionally, high-risk patient groups of thromboembolism or abnormal proliferation of the endometrium that cannot use tamoxifen, may use this product.

As the first-line treatment for patients with positive postmenopausal estrogen receptors, undefined late phase or metastatic breast cancer.

Postmenopausal women with late phase breast cancer, negative estrogen receptors, but reacted positively with tamoxifen treatment.

Product Name
Docetaxel
Product Description

Docetaxel in combination with doxorubicin and cyclophosphamide is indicated for the adjuvant treatment of patients with: - operable node-positive breast cancer. -operable node-negative breast cancer.

Docetaxel in combination with cisplatin and 5-fluorouracil is indicated for the treatment of patients with metastatic gastric adenocarcinoma, including adenocarcinoma of the gastroesophageal junction, who have not received prior chemotherapy for metastatic disease. Head and Neck Cancer: Docetaxel in combination with cisplatin and 5-fluorouracil is indicated for the induction treatment of patients with locally advanced squamous cell carcinoma of the head and neck.

Product Name
Voriconazole 200MG INJECTION
Product Description

Invasive aspergillosis, serious invasive Candida infections, and serious infections caused by Scedosporium spp. and Fusarium spp. 

Product Name
Liposomal Amphotericin B for Injection
Product Description

Figure: Human pharmacokinetic results of Lipo-AB and AmBisome®

R-Mean: AmBisome®

T-Mean: Lipo-AB

Human pharmacokinetic results are similar to reference drug as shown as Figure.

 

Liposomal Amphotericin B for Injection is a liposomal form of amphotericin B used to treat fungal infections caused by Aspergillus, Candida and Cryptococcus. Due to the smaller size, higher transition temperature and more rigid bilayer of the liposome, it finally provides a persistent pool of liposomal Amphotericin B in plasma and a sustained delivery to the site of infection.

The in-vitro and in-vivo studies showthe similar drug release profile were obtained between Ambisome® and Lipo-AB.

TTY’s Lipo-AB provides the following advantages:

  • solid in-vitro and in-vivo data support
  • no patent infringement
  • compliance with cGMP
  • US CTD dossier available